Release of molecules from nanocarriers

نویسندگان

چکیده

Release of drug or vaccine molecules from macro-, micro-, and nano-sized carriers is usually considered to be limited by diffusion and/or carrier dissolution erosion. The corresponding experimentally observed kinetics...

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Continuous release of gentamicin from gold nanocarriers

Antibiotics are still the most effective agents used to fight bacterial infections. Antibiotics are quickly metabolised or excreted from the human body, thus they need to be frequently administered (a few times a day) and their half life is usually an important factor in the therapeutic choice. In order to render the administration less frequent, antibiotic release from a carrier can be employe...

متن کامل

Modeling the Release Kinetics of Poorly Water-Soluble Drug Molecules from Liposomal Nanocarriers

Liposomes are frequently used as pharmaceutical nanocarriers to deliver poorly water-soluble drugs such as temoporfin, cyclosporine A, amphotericin B, and paclitaxel to their target site. Optimal drug delivery depends on understanding the release kinetics of the drug molecules from the host liposomes during the journey to the target site and at the target site. Transfer of drugs in model system...

متن کامل

Modeling Drug-Carrier Interaction in the Drug Release from Nanocarriers

Numerous nanocarriers of various compositions and geometries have been developed for the delivery and release of therapeutic and imaging agents. Due to the high specific surface areas of nanocarriers, different mechanisms such as ion pairing and hydrophobic interaction need to be explored for achieving sustained release. Recently, we developed a three-parameter model that considers reversible d...

متن کامل

Study of Mesoporous Silica Nanoparticles as Nanocarriers for Sustained Release of Curcumin

Curcumin (CUR) is a hydrophobic molecule and beneficial antioxidant with known anticancer property. The bioavailability of curcumin is low because of its hydrophobic structure. Mesoporous silica nanoparticles (MSN) loaded by CUR were used as nanocarriers for sustained release of CUR in four different media such as simulated gastric,intestinal, colon and body fluids (SGF, SIF, SCF, and SBF, ...

متن کامل

Targeted Brain Delivery of Bioactive Molecules Using Nanocarriers

The brain is the center of the nervous system and an integral part of the body acting as a major regulating and conveying organ to maintain the body’s homeostasis in response to changes in both the external and internal surroundings. Brain consists of approximately 100 billion neurons and 1 trillion glial cells [1]. The connection between two neurons is known as synapse, which are responsible f...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Physical Chemistry Chemical Physics

سال: 2023

ISSN: ['1463-9076', '1463-9084']

DOI: https://doi.org/10.1039/d3cp01855e